I get seasick in a bath. Had a VERY rough crossing of the Drake Passage and ended up with the doc or nurse in my stateroom every hour on the hour, was on an IV for the first 2 days, fortunately finally got my sea legs the day we arrived got to Antarctica. Sailed to Pitcairn Island on the supply ship, had the patch, band, and seasickness pills and only threw up once 😄
I also got a shot on the QE2, Phenergan, and it worked a treat - but yes, have the shot at night. Doing a world cruise in 2024 and definitely going to line up for a shot first night just in case.