We are on the Panama Canal and Central America cruise, so we should be ok. We are only in Mexico and Belize before Roatan.  This is what I had found regarding Honduras requirements. Not from Viking: Vaccines If you’re traveling from Argentina, Bolivia, Brasil, Colombia, Ecuador, Guyana, French Guiana, Panamá, Paraguay, Perú, Surinam, Trinidad and Tobago or Venezuela, you must first get vaccinated against yellow fever.  Also if you’re coming from Angola, Benin, Burkina Faso, Burundi