Readily accessible memorable scenery: Kotor, Amalfi, Catania
Be aware that this is an Adriatic Sea intensive cruise. Personally I like the Adriatic towns/ports and you don't spend your time being dragged from one Roman ruin to the next.
Eastern Med is mainly Greece and Turkey. Many areas are mountainous and have scenic beaches. Very pretty but can involve a lot of walking.
But Kotor (sail in and "fjord"), Amalfi (coastal tour to Positano by boat, or take the coastal road), and Catania (Mt. Etna) are unique in the world.
All comments are just my experience and preferences.